Frontal white matter choline-containing compounds increase with alcohol consumption and glutamate decreases with increasing addiction criteria
نویسندگان
چکیده
It has been previously shown that frontal white matter (fWM) choline-containing compounds (tCho) increase with alcohol consumption in social drinkers but were found decreased in detoxified alcoholics [1,2]. With this study we aimed to investigate whether fWM tCho would still be elevated in heavy drinking as well as in non-abstinent alcohol dependent patients. Since Glutamate plays an important role in alcoholism [3] we further investigated correlations between glutamate concentrations and measures of alcohol addiction. Methods
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